EPITALON

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Epitalon (also known as Epithalamin or Epithalon) is a synthetic tetrapeptide derived from a naturally occurring compound in the pineal gland.

Its amino acid sequence — Ala–Glu–Asp–Gly — was originally discovered by Professor Vladimir Khavinson and has been widely studied for its potential anti-aging, telomere-lengthening, and pineal regulatory effects.

Epitalon is often described in research as a “bioregulatory peptide” that helps restore natural circadian rhythms, support DNA stability, and optimize overall longevity mechanisms.

Epitalon exerts its effects through gene regulation, telomerase activation, and antioxidant pathways, contributing to healthier cellular aging and repair.

Key mechanisms observed in research:

1. Activates telomerase enzyme – helps maintain and extend telomere length
    
2. Regulates melatonin secretion – restores circadian rhythm and sleep cycles
    
3. Enhances DNA repair – supports genomic stability and protein synthesis
    
4. Improves mitochondrial function – boosts cellular energy efficiency
    
5. Supports hormonal balance – harmonizes endocrine signaling linked to aging
    

Longevity research

Lengthened telomeres and delayed cellular senescence

Sleep and circadian health

Improved melatonin regulation and sleep quality

DNA protection

Reduced oxidative and genotoxic stress

Immune support

Balanced cytokine response and improved resilience

Systemic vitality

Enhanced physical and cognitive function in aging models

Injectable (subcutaneous)

5–10 mg daily

10–20 days per research cycle

Oral / Sublingual form

5–10 mg daily

10–20 days per cycle

Maintenance cycles

2–3 times per year

Based on study design

• Half-life: Short (~20 minutes), biological effects may persist longer
   
• Cycle duration: Commonly 10–20 days per research phase
   
• Synergistic research: Frequently studied alongside Pinealon or Thymosin Alpha-1