GHRP-2/6

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GHRP-2 and GHRP-6 (Growth Hormone Releasing Peptides 2 & 6) are synthetic hexapeptides that belong to the Ghrelin receptor agonist family.

Both act on the GHS-R1a receptor to stimulate the pituitary gland to release endogenous Growth Hormone (GH).

They differ slightly in potency and side-effect profile:

• GHRP-2 → Stronger GH release, less appetite stimulation
   
• GHRP-6 → Moderate GH release, stronger appetite and GH pulse synergy
   

These peptides are frequently studied alongside GHRH analogues such as CJC-1295 or Sermorelin for amplified GH and IGF-1 responses.

Both peptides mimic the natural hunger hormone Ghrelin, activating the hypothalamus and pituitary to promote pulsatile growth hormone release while minimizing suppression of endogenous feedback loops.

1.  Stimulate GH and IGF-1 secretion
    
2. Enhance appetite and nutrient absorption (GHRP-6)
    
3. Increase protein synthesis and tissue repair
    
4. Improve sleep-linked GH pulses and recovery
    
5. Support metabolic balance and fat metabolism
    

GH stimulation

Elevated natural GH & IGF-1 levels

Muscle recovery

Enhanced protein synthesis & healing

Metabolic efficiency

Improved fat oxidation & energy balance

Sleep & regeneration

Deeper sleep and faster tissue repair

Anti-aging research

Supported pituitary responsiveness and vitality

GHRP-2

100–300 mcg

1–3× daily

Potent GH release, minimal hunger response

GHRP-6

100–300 mcg

1–3× daily

Stimulates appetite, enhances GH pulse

CJC-1295 / Sermorelin Stack

100 mcg each

Same time as GHRP

Synergistic GH amplitude boost

• Timing: Often administered pre-sleep or fasted in research to match natural GH rhythms
   
• Cycle duration: 8–12 weeks
   
• Half-life: ~15–30 minutes (rapid-acting, pulsatile effect)