IPAMORELIN

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Ipamorelin is a selective Growth Hormone Secretagogue (GHS) and Ghrelin receptor agonist that stimulates the body’s natural release of Growth Hormone (GH) from the pituitary gland.

It is one of the most refined GHRP-class peptides, designed to provide a clean, controlled GH pulse with minimal side effects — showing strong results in anti-aging, recovery, and metabolic research.

Ipamorelin mimics the natural hunger hormone Ghrelin, binding to GHS-R1a receptors in the pituitary and hypothalamus to trigger growth hormone release.

Unlike earlier secretagogues (like GHRP-6 or GHRP-2), it produces no significant increase in cortisol or prolactin, making it one of the most targeted GH-releasing peptides in research.

Key mechanisms observed in studies:

1. Stimulates GH secretion via ghrelin receptor activation
    
2. Supports muscle repair and lean mass growth
    
3. Enhances fat metabolism and recovery processes
    
4. Improves deep sleep and recovery hormone cycles
    
5. Promotes neuroendocrine balance through pituitary regulation
    

Growth hormone release

Pulsatile, physiological GH and IGF-1 elevation

Muscle recovery

Enhanced protein synthesis and repair

Fat metabolism

Improved lipid oxidation and energy efficiency

Sleep and regeneration

Deeper sleep cycles and cellular repair

Anti-aging research

Pituitary support and hormonal balance

 Injectable (subcutaneous)

100–300 mcg daily

Once or twice daily

Stacked with Sermorelin or CJC-1295

100 mcg of each peptide

Administered together at night

• Cycle duration (research): 8–12 weeks
   
• Half-life: ~2 hours (rapid onset and short systemic activity)
   
• Synergistic research: Frequently studied with Sermorelin, CJC-1295, or GHRP-2 for enhanced GH amplitude