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PINEALON

What is Pinealon?

Pinealon is a short synthetic tripeptide composed of Glu–Asp–Arg (Glutamic acid, Aspartic acid, Arginine).

It was developed as a neuroprotective and cognitive-support peptide, originally researched by the St. Petersburg Institute of Bioregulation and Gerontology.

Studies suggest that Pinealon may help protect neurons, regulate gene expression, and support healthy brain function and longevity, especially under oxidative or metabolic stress.

How It Works

Pinealon acts on gene expression and protein synthesis pathways involved in neural repair, antioxidant defense, and cognitive function.

Key mechanisms observed in research:

  1. Enhances neuronal metabolism – improves oxygen and glucose utilization in brain cells
     
  2. Regulates gene expression – supports DNA/RNA synthesis and repair
     
  3. Protects neurons from oxidative damage – reduces free radical activity
     
  4. Improves sleep and circadian balance – linked to pineal gland and melatonin regulation
     
  5. Supports memory and learning – increases synaptic signaling efficiency
     

Potential Research Benefits

Cognitive support

Enhanced learning, memory, and focus


Neuroprotection

Reduced oxidative and ischemic damage


Sleep regulation

Supported circadian rhythm and melatonin pathways


Anti-aging

Improved gene repair and mitochondrial efficiency


Mood balance

Stabilized neurological and emotional function

Dosing

Injectable (subcutaneous or intramuscular)

100–300 mcg daily

Once daily


Oral or capsule form (experimental)

100–300 mcg daily

Once daily


  • Cycle duration (research): 10–20 days, sometimes extended to 30
     
  • Half-life: Short (~30 minutes, fast-acting)
     
  • Synergy: Commonly researched with Cortexin, Epitalon, or Semax for cumulative neuroprotective benefits

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