SELANK

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 Selank is a synthetic heptapeptide (seven amino acids) derived from the natural human tetrapeptide Tuftsin, a molecule involved in immune regulation.

It was originally developed by the Institute of Molecular Genetics in Russia as a nootropic and anxiolytic peptide, studied for its ability to reduce stress, improve focus, and enhance mood stability.

Selank is a non-sedative, non-addictive compound, often described in research as a “peptide-based alternative to traditional anxiolytics.”

 Selank acts primarily on neuromodulation and neurochemical balance, influencing several key systems in the brain:

1. Modulates GABA receptors – promotes calmness and anxiety reduction
    
2. Increases serotonin and dopamine stability – enhances mood and focus
    
3. Supports BDNF expression – aids neuroplasticity and cognitive resilience
    
4. Regulates immune and cytokine balance – reduces stress-induced inflammation
    
5. Improves sleep quality – indirectly through anxiolytic and neurochemical effects
    

Together, these actions make Selank a key research peptide in studies related to anxiety, stress resilience, and cognitive optimization.

Anxiolytic

Reduced stress and anxiety responses

Cognitive function

Improved memory, learning, and focus

Mood regulation

Balanced dopamine and serotonin activity

Immune modulation

Stabilized cytokine and immune signaling

Neuroprotection

Increased BDNF and neuronal repair markers

Nasal spray

250–500 mcg per spray

1–2 times daily

Injectable (subcutaneous)

250–500 mcg

1–2 times daily

Oral/sublingual form (experimental)

250–1000 mcg

1–2 times daily

• Cycle duration (research): 2–4 weeks (short-term cognitive studies)
   
• Half-life: ~5–10 minutes (rapid onset, short systemic duration)
   
• Mechanistic synergy: Often studied with Semax or Selank + BDNF modulators
   

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